← All NFL picks for Thursday, September 25, 2025

Seattle Seahawks vs Arizona Cardinals

Thursday, September 25, 2025 — NFL Prediction & Pick

This matchup is essentially a toss-up

The model sees this as a true toss-up between Seattle Seahawks and Arizona Cardinals. The projected margin is SEA by 0.4 points. That lean is driven mainly by market line and context.

On balance, more tracked inputs leaned Seattle Seahawks (2 edges vs 0 for Arizona Cardinals).

The model's lean lines up with that edge count. The score model and the raw stat comparison point the same way.

Matchup Breakdown

Market line — leans Seattle Seahawks

Market line is a large contribution and supports SEA by about 1.0 points of margin. The market spread feature is +1.5.

Context — leans Seattle Seahawks

Context is a large contribution and supports SEA by about 0.5 points of margin.

Betting Lines

Arizona Cardinals +1.0 (Pinnacle) | O/U 43.5 (LowVig.ag)

Final Score

Seattle Seahawks 23, Arizona Cardinals 20 — Seattle Seahawks win

This analysis is generated by a statistical model and is intended for informational and entertainment purposes only. It does not constitute financial or betting advice. Past model performance does not guarantee future results. Please gamble responsibly.