← All NFL picks for Thursday, September 18, 2025

Miami Dolphins vs Buffalo Bills

Thursday, September 18, 2025 — NFL Prediction & Pick

Our model leans Buffalo Bills
strong lean

The model leans Buffalo Bills primarily because of advantages in Market line and Form. The projected margin is BUF by 9.8 points. That lean is driven mainly by market line and form. Context pulls the other way.

On balance, more tracked inputs leaned Buffalo Bills (2 edges vs 1 for Miami Dolphins).

The model's lean lines up with that edge count. The score model and the raw stat comparison point the same way.

Matchup Breakdown

Market line — leans Buffalo Bills

Market line is a large contribution and supports BUF by about 6.3 points of margin. The market spread feature is -11.5.

Form — leans Buffalo Bills

Form is a large contribution and supports BUF by about 1.1 points of margin. Points scored per game: BUF 31.7, MIA 21.1.

Context — leans Miami Dolphins

Context pulls the other way and favors MIA by about 0.4 points of margin.

Betting Lines

Buffalo Bills -11.5 (BetMGM) | O/U 50.5 (Pinnacle)

Final Score

Miami Dolphins 21, Buffalo Bills 31 — Buffalo Bills win — Model pick was correct

This analysis is generated by a statistical model and is intended for informational and entertainment purposes only. It does not constitute financial or betting advice. Past model performance does not guarantee future results. Please gamble responsibly.