Pittsburgh Pirates vs St. Louis Cardinals

August 26, 2025 — MLB Prediction & Betting Pick

Our model leans Pittsburgh Pirates

On balance, more tracked inputs leaned Pittsburgh Pirates (12 edges vs 11 for St. Louis Cardinals).

The model's lean aligns with the overall edge count. Both the machine-learning model and the raw feature comparison point the same direction for this game.

Matchup Breakdown

Recent form (last ~10 games) — leans Pittsburgh Pirates

Looking at recent performance trends over the last ten games — including win rate, run differential, and offensive momentum — the matchup favors the Pittsburgh Pirates.

St. Louis Cardinals 0.450 vs Pittsburgh Pirates 0.450 — roughly even
St. Louis Cardinals -1.10 vs Pittsburgh Pirates -1 — roughly even
St. Louis Cardinals 4.40 vs Pittsburgh Pirates 3.70 — leans St. Louis Cardinals
St. Louis Cardinals 5.50 vs Pittsburgh Pirates 4.70 — leans Pittsburgh Pirates
St. Louis Cardinals 0.333 vs Pittsburgh Pirates 0.667 — leans Pittsburgh Pirates
St. Louis Cardinals 1.136 vs Pittsburgh Pirates 1.351 — leans Pittsburgh Pirates

Season to date — leans St. Louis Cardinals

Season-long stats including runs scored and allowed per game, home/road splits, and weighted offensive production (wRC+) the matchup favors the St. Louis Cardinals.

St. Louis Cardinals 4.20 vs Pittsburgh Pirates 3.56 — leans St. Louis Cardinals
St. Louis Cardinals 4.43 vs Pittsburgh Pirates 4.09 — leans Pittsburgh Pirates
St. Louis Cardinals 0.400 vs Pittsburgh Pirates 0.143 — leans St. Louis Cardinals
St. Louis Cardinals 97.1 vs Pittsburgh Pirates 91.0 — leans St. Louis Cardinals

Starting pitching (recent starts) — Mixed

The starting pitching matchup between Pittsburgh Pirates and St. Louis Cardinals grades out as a toss-up based on recent outings.

St. Louis Cardinals 6.38 vs Pittsburgh Pirates 9.45 — leans St. Louis Cardinals
St. Louis Cardinals 1.58 vs Pittsburgh Pirates 2.25 — leans St. Louis Cardinals
St. Louis Cardinals 7.50 vs Pittsburgh Pirates 8.55 — leans Pittsburgh Pirates
St. Louis Cardinals -7.54 vs Pittsburgh Pirates -1.38 — leans St. Louis Cardinals
St. Louis Cardinals 4.57 vs Pittsburgh Pirates 3.20 — leans Pittsburgh Pirates
St. Louis Cardinals 1.62 vs Pittsburgh Pirates 0.83 — leans Pittsburgh Pirates
St. Louis Cardinals 4.90 vs Pittsburgh Pirates 2.82 — leans Pittsburgh Pirates
St. Louis Cardinals 18.7 vs Pittsburgh Pirates 19.7 — leans St. Louis Cardinals

Offense & matchup — Mixed

The offensive matchup is closely contested between Pittsburgh Pirates and St. Louis Cardinals.

St. Louis Cardinals 0.361 vs Pittsburgh Pirates 0.368 — roughly even
St. Louis Cardinals 0.429 vs Pittsburgh Pirates 0.447 — roughly even
St. Louis Cardinals 0.334 vs Pittsburgh Pirates 0.425 — leans Pittsburgh Pirates
St. Louis Cardinals 0.414 vs Pittsburgh Pirates 0.561 — leans Pittsburgh Pirates
St. Louis Cardinals 0.387 vs Pittsburgh Pirates 0.358 — leans St. Louis Cardinals
St. Louis Cardinals 0.483 vs Pittsburgh Pirates 0.425 — leans St. Louis Cardinals
St. Louis Cardinals 0.435 vs Pittsburgh Pirates 0.563 — leans Pittsburgh Pirates
St. Louis Cardinals 0.026 vs Pittsburgh Pirates -0.010 — leans St. Louis Cardinals

Series & head-to-head — leans Pittsburgh Pirates

Prior head-to-head meetings this season's training window — win rate and run differential between these clubs — the matchup favors the Pittsburgh Pirates.

St. Louis Cardinals 0.500 vs Pittsburgh Pirates 0.500 — roughly even
St. Louis Cardinals -0.60 vs Pittsburgh Pirates 0.60 — leans Pittsburgh Pirates

Betting Lines

St. Louis Cardinals -1.5 | O/U 8.5 (FanDuel)

Final Score

Pittsburgh Pirates 8, St. Louis Cardinals 3 — Pittsburgh Pirates win — Model pick was correct

This analysis is generated by a machine-learning model and is intended for informational and entertainment purposes only. It does not constitute financial or betting advice. Past model performance does not guarantee future results. Please gamble responsibly.