Pittsburgh Pirates vs St. Louis Cardinals

May 7, 2025 — MLB Prediction & Betting Pick

Our model leans St. Louis Cardinals

On balance, more tracked inputs leaned St. Louis Cardinals (19 edges vs 1 for Pittsburgh Pirates).

The model's lean aligns with the overall edge count. Both the machine-learning model and the raw feature comparison point the same direction for this game.

Matchup Breakdown

Recent form (last ~10 games) — leans St. Louis Cardinals

Looking at recent performance trends over the last ten games — including win rate, run differential, and offensive momentum — the matchup favors the St. Louis Cardinals.

St. Louis Cardinals 0.450 vs Pittsburgh Pirates 0.300 — leans St. Louis Cardinals
St. Louis Cardinals -0.25 vs Pittsburgh Pirates -1.55 — leans St. Louis Cardinals
St. Louis Cardinals 3.70 vs Pittsburgh Pirates 2.90 — leans St. Louis Cardinals
St. Louis Cardinals 3.95 vs Pittsburgh Pirates 4.45 — leans St. Louis Cardinals
St. Louis Cardinals 1 vs Pittsburgh Pirates 0 — leans St. Louis Cardinals
St. Louis Cardinals 1.171 vs Pittsburgh Pirates 0.460 — leans St. Louis Cardinals

Season to date — leans St. Louis Cardinals

Season-long stats including runs scored and allowed per game, home/road splits, and weighted offensive production (wRC+) the matchup favors the St. Louis Cardinals.

St. Louis Cardinals 4.22 vs Pittsburgh Pirates 3.19 — leans St. Louis Cardinals
St. Louis Cardinals 4.17 vs Pittsburgh Pirates 4.59 — leans St. Louis Cardinals
St. Louis Cardinals 0.667 vs Pittsburgh Pirates 0.375 — leans St. Louis Cardinals
St. Louis Cardinals 102.2 vs Pittsburgh Pirates 88.5 — leans St. Louis Cardinals

Starting pitching (recent starts) — leans St. Louis Cardinals

Evaluating the probable starters based on recent ERA, WHIP, strikeout rate, and pitching form trends, the matchup favors the St. Louis Cardinals.

St. Louis Cardinals 3.49 vs Pittsburgh Pirates 3.38 — roughly even
St. Louis Cardinals 1.27 vs Pittsburgh Pirates 1.19 — roughly even
St. Louis Cardinals 7.62 vs Pittsburgh Pirates 6.44 — leans St. Louis Cardinals
St. Louis Cardinals -2.51 vs Pittsburgh Pirates 0.79 — leans St. Louis Cardinals
St. Louis Cardinals 1.73 vs Pittsburgh Pirates 6.10 — leans St. Louis Cardinals
St. Louis Cardinals 0.96 vs Pittsburgh Pirates 1.40 — leans St. Louis Cardinals
St. Louis Cardinals 2.87 vs Pittsburgh Pirates 3.58 — leans St. Louis Cardinals
St. Louis Cardinals 31 vs Pittsburgh Pirates 20.7 — leans Pittsburgh Pirates

Offense & matchup — leans St. Louis Cardinals

Analyzing recent offensive output (OBP, SLG) and platoon matchup data against the opposing starter's throwing arm, the matchup favors the St. Louis Cardinals.

St. Louis Cardinals 0.376 vs Pittsburgh Pirates 0.374 — roughly even
St. Louis Cardinals 0.427 vs Pittsburgh Pirates 0.416 — roughly even
St. Louis Cardinals 0.415 vs Pittsburgh Pirates 0.376 — leans St. Louis Cardinals
St. Louis Cardinals 0.490 vs Pittsburgh Pirates 0.355 — leans St. Louis Cardinals
St. Louis Cardinals 0.396 vs Pittsburgh Pirates 0.394 — roughly even
St. Louis Cardinals 0.456 vs Pittsburgh Pirates 0.451 — roughly even
St. Louis Cardinals 0.539 vs Pittsburgh Pirates 0.563 — roughly even
St. Louis Cardinals 0.020 vs Pittsburgh Pirates 0.020 — roughly even

Series & head-to-head — leans St. Louis Cardinals

Prior head-to-head meetings this season's training window — win rate and run differential between these clubs — the matchup favors the St. Louis Cardinals.

St. Louis Cardinals 0.600 vs Pittsburgh Pirates 0.400 — leans St. Louis Cardinals
St. Louis Cardinals 0.20 vs Pittsburgh Pirates -0.20 — leans St. Louis Cardinals

Betting Lines

St. Louis Cardinals -1.5 | O/U 7.5 (FanDuel)

Final Score

Pittsburgh Pirates 0, St. Louis Cardinals 5 — St. Louis Cardinals win — Model pick was correct

This analysis is generated by a machine-learning model and is intended for informational and entertainment purposes only. It does not constitute financial or betting advice. Past model performance does not guarantee future results. Please gamble responsibly.