Milwaukee Brewers vs St. Louis Cardinals

April 26, 2025 — MLB Prediction & Betting Pick

Our model leans St. Louis Cardinals

On balance, more tracked inputs leaned St. Louis Cardinals (14 edges vs 10 for Milwaukee Brewers).

The model's lean aligns with the overall edge count. Both the machine-learning model and the raw feature comparison point the same direction for this game.

Matchup Breakdown

Recent form (last ~10 games) — leans Milwaukee Brewers

Looking at recent performance trends over the last ten games — including win rate, run differential, and offensive momentum — the matchup favors the Milwaukee Brewers.

St. Louis Cardinals 0.350 vs Milwaukee Brewers 0.500 — leans Milwaukee Brewers
St. Louis Cardinals -0.50 vs Milwaukee Brewers 1.85 — leans Milwaukee Brewers
St. Louis Cardinals 3.60 vs Milwaukee Brewers 5.50 — leans Milwaukee Brewers
St. Louis Cardinals 4.10 vs Milwaukee Brewers 3.65 — leans Milwaukee Brewers
St. Louis Cardinals 0.667 vs Milwaukee Brewers 0 — leans St. Louis Cardinals
St. Louis Cardinals 1.296 vs Milwaukee Brewers 0.545 — leans St. Louis Cardinals

Season to date — leans St. Louis Cardinals

Season-long stats including runs scored and allowed per game, home/road splits, and weighted offensive production (wRC+) the matchup favors the St. Louis Cardinals.

St. Louis Cardinals 4.56 vs Milwaukee Brewers 4.96 — leans Milwaukee Brewers
St. Louis Cardinals 4.44 vs Milwaukee Brewers 4.52 — roughly even
St. Louis Cardinals 0.714 vs Milwaukee Brewers 0.364 — leans St. Louis Cardinals
St. Louis Cardinals 100.5 vs Milwaukee Brewers 96.3 — leans St. Louis Cardinals

Starting pitching (recent starts) — leans Milwaukee Brewers

Evaluating the probable starters based on recent ERA, WHIP, strikeout rate, and pitching form trends, the matchup favors the Milwaukee Brewers.

St. Louis Cardinals 3.41 vs Milwaukee Brewers 3.52 — roughly even
St. Louis Cardinals 0.86 vs Milwaukee Brewers 1.35 — leans St. Louis Cardinals
St. Louis Cardinals 9 vs Milwaukee Brewers 5.87 — leans St. Louis Cardinals
St. Louis Cardinals 3.94 vs Milwaukee Brewers 3.47 — leans Milwaukee Brewers
St. Louis Cardinals 9.39 vs Milwaukee Brewers 4.50 — leans Milwaukee Brewers
St. Louis Cardinals 1.89 vs Milwaukee Brewers 1.25 — leans Milwaukee Brewers
St. Louis Cardinals 6.88 vs Milwaukee Brewers 4.55 — leans Milwaukee Brewers
St. Louis Cardinals 10.7 vs Milwaukee Brewers 17 — leans St. Louis Cardinals

Offense & matchup — leans St. Louis Cardinals

Analyzing recent offensive output (OBP, SLG) and platoon matchup data against the opposing starter's throwing arm, the matchup favors the St. Louis Cardinals.

St. Louis Cardinals 0.380 vs Milwaukee Brewers 0.384 — roughly even
St. Louis Cardinals 0.439 vs Milwaukee Brewers 0.460 — leans Milwaukee Brewers
St. Louis Cardinals 0.405 vs Milwaukee Brewers 0.368 — leans St. Louis Cardinals
St. Louis Cardinals 0.447 vs Milwaukee Brewers 0.377 — leans St. Louis Cardinals
St. Louis Cardinals 0.414 vs Milwaukee Brewers 0.379 — leans St. Louis Cardinals
St. Louis Cardinals 0.521 vs Milwaukee Brewers 0.484 — leans St. Louis Cardinals
St. Louis Cardinals 0.551 vs Milwaukee Brewers 0.533 — roughly even
St. Louis Cardinals 0.033 vs Milwaukee Brewers -0.005 — leans St. Louis Cardinals

Series & head-to-head — leans St. Louis Cardinals

Prior head-to-head meetings this season's training window — win rate and run differential between these clubs — the matchup favors the St. Louis Cardinals.

St. Louis Cardinals 1 vs Milwaukee Brewers 0 — leans St. Louis Cardinals
St. Louis Cardinals 1 vs Milwaukee Brewers -1 — leans St. Louis Cardinals

Betting Lines

St. Louis Cardinals -1.5 | O/U 7.5 (FanDuel)

Final Score

Milwaukee Brewers 5, St. Louis Cardinals 6 — St. Louis Cardinals win — Model pick was correct

This analysis is generated by a machine-learning model and is intended for informational and entertainment purposes only. It does not constitute financial or betting advice. Past model performance does not guarantee future results. Please gamble responsibly.